Search results for "White matter abnormalities"

showing 3 items of 3 documents

The effect of age on cognitive performance of frontal patients

2015

Age is known to affect prefrontal brain structure and executive functioning in healthy older adults, patients with neurodegenerative conditions and TBI. Yet, no studies appear to have systematically investigated the effect of age on cognitive performance in patients with focal lesions. We investigated the effect of age on the cognitive performance of a large sample of tumour and stroke patients with focal unilateral, frontal (n=68), or non-frontal lesions (n=45) and healthy controls (n=52). We retrospectively reviewed their cross sectional cognitive and imaging data. In our frontal patients, age significantly predicted the magnitude of their impairment on two executive tests (Raven's Advanc…

AdultMaleAgingRAPM Raven's Advanced Progressive MatricesCognitive NeuroscienceExperimental and Cognitive Psychologybehavioral disciplines and activitiesArticleTBI traumatic brain injuryCVA cerebrovascular accidentExecutive functionsBehavioral NeuroscienceExecutive FunctionPFC prefrontal cortexCognitionArts and Humanities (miscellaneous)WMA white matter abnormalitiesIL Incomplete Letters andAging; Cognitive performance; Executive functions; Frontal lesions non-frontal lesions; Behavioral Neuroscience; Cognitive Neuroscience; Experimental and Cognitive Psychology; Arts and Humanities (miscellaneous)Frontal lesions non-frontal lesionnon-frontal lesionsHumansHC healthy controlsCognitive performanceRetrospective StudiesCWMA Composite White Matter AbnormalitiesFrontal lesionsBrain NeoplasmsGNT Graded Naming TestAge FactorsBrainMiddle AgedFrontal LobeStrokeFrontal lesions non-frontal lesionsIQ Intelligence QuotientStroop TestFemaleNART National Adult Reading TestNeuropsychologia
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2019

Objective: Severe malnutrition in patients with anorexia nervosa (AN) as well as possible trait-related aberrations lead to pronounced structural brain changes whose reversibility after recovery is currently unclear. Previous diffusion tensor imaging (DTI) studies investigating white matter (WM) microstructure alterations in AN are inconsistent. Methods: In this so far largest DTI study in adults, we investigated 33 AN patients, 20 recovered (REC), and 33 healthy women. DTI data were processed using the "DTI and Fiber tools," and the Computational Anatomy Toolbox. WM integrity, both in terms of fractional anisotropy (FA) and mean diffusivity (MD), was assessed. Results: We found a significa…

Pathologymedicine.medical_specialtybusiness.industryCorpus callosumThalamic radiation030227 psychiatryWhite matter03 medical and health sciencesPsychiatry and Mental health0302 clinical medicinemedicine.anatomical_structureAnorexia nervosa (differential diagnoses)Fractional anisotropymedicineWhite matter abnormalitiesIn patientbusiness030217 neurology & neurosurgeryDiffusion MRIFrontiers in Psychiatry
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58. White matter abnormalities in attention-deficit/hyperactivity disorder: A diffusion tensor imaging study in adult patients

2009

Pediatricsmedicine.medical_specialtyAdult patientsbusiness.industrymedicine.diseaseSensory SystemsNeurologyPhysiology (medical)medicineWhite matter abnormalitiesAttention deficit hyperactivity disorderNeurology (clinical)businessDiffusion MRIClinical Neurophysiology
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